Electroencephalography and analgesics

Electroencephalography

Recent advances in electroencephalography (EEG) research are presented. Particular emphasis is placed on sleep and epilepsy research in humans. In this context, among others, studies on the modifications of EEG epileptic activity during sleep are discussed in more detail. A large number of reports come from EEG monitoring during presurgical evaluation and surgical treatment of drug-resistant ep...

Electroencephalography.

Analgesics and kidney disease.

The National Institutes of Health (NIH) recently issued a report stating that 'combinations of antipyretic analgesics, taken in large doses over a prolonged period, cause a specific form of kidney disease and chronic renal failure.' This hypothesis has been widely held for many years. The NIH report may faithfully describe the consensus in medicine today, but it is not informative about what is...

Opioid and Nonopioid Analgesics

SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF N-METHYL PIPERIDINE ANALGESICS

Pain is probably the immediate stimulus for more visits to the Physician's office than all other complaints combined. Since pain serves as an alert to injury, it is often the first harbinger of disease. Piperidine has been extensively utilized for the synthesis of a wide range of therapeutic agents in general and analgetics in particular for the mitigation of pain. In a similar attempt, th...